Table 2. Analysis of risk factors for AE.
| Variables | Asthma exacerbation | Adjusted OR | ||
|---|---|---|---|---|
| No (%) | Yes (%) | (95% CI) | P-value | |
| Antipyretics* | ||||
| Acetaminophen | 564 (60.9) | 27 (47.4) | Reference | |
| Ibuprofen | 362 (39.1) | 30 (52.6) | 2.10 [1.17–3.76] | 0.01 |
| Age, year (SD) | 4.1 (0.9) | 3.8 (0.9) | 0.80 [0.60–1.07] | 0.13 |
| Sex | ||||
| Female | 346 (37.4) | 21 (36.8) | Reference | |
| Male | 580 (62.6) | 36 (63.2) | 1.03 [0.57–1.86] | 0.93 |
| Patient status in the previous year | ||||
| Asthma AEǂ | ||||
| No | 846 (91.4) | 29 (50.9) | Reference | |
| Yes | 80 (8.6) | 28 (49.1) | 10.6 [5.90–18.9] | <0.0001 |
| Use of systemic corticosteroids# | ||||
| No | 547 (59.1) | 13 (22.8) | Reference | |
| Yes | 379 (40.9) | 44 (77.2) | 3.07 [1.56–6.05] | 0.001 |
Notes:
*
Adjusted for age, sex, and patient status in the previous year (AE and use of systemic corticosteroids).
ǂ
Adjusted for age, sex, and AE in the previous year.
#
Adjusted for age, sex, and use of systemic corticosteroids in the previous year.
OR, odds ratios; CI, confidence intervals.