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LTP in the CA1–Schaffer collateral pathway of hippocampal slices in the presence of caged (▴) or unmodified (□) BDNF-Ab (concentration 2 μg/ml). After TBS (indicated by the ▾ symbol), synaptic potentiation was significantly larger in slices treated with caged Ab compared with unmodified Ab. Inset depicts two EPSP traces for the caged Ab experiment, 10 min before (thin trace) and 60 min after (thick trace) TBS.
