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. 2019 Apr 19;14(4):e0215033. doi: 10.1371/journal.pone.0215033

Fig 6. Effect of GSK2256294 on cytokine release from UC and CD colon explants measured by ELISA.

Fig 6

UC or CD tissue samples were incubated for 18 h with varying doses of GSK2256294 (294), or prednisolone (positive control). GSK2256294 doses are in nM. Cytokine release in the cell-free supernatant was determined by ELISA as described in Material and Methods and were normalized to DMSO (negative control). Samples from N = 6 UC and N = 10 CD donors were used in the cytokine analysis. Error bars represent standard errors. * denotes p<0.05 vs DMSO control.