Table 1. Clinicopathological characteristics of the patients.
Features | MSI-H | MSS | Total | P value |
---|---|---|---|---|
Total | 29 | 907 | 936 | |
Gender | 0.022 | |||
Male | 10 | 514 | 524 | |
Female | 19 | 393 | 412 | |
Age (years old) | 0.007 | |||
≦69 | 9 | 516 | 525 | |
≧70 | 20 | 391 | 411 | |
Location | <0.0001 | |||
Right a | 24 | 220 | 244 | |
Left b | 5 | 687 | 692 | |
Histology | <0.0001 | |||
wel/mod c | 16 | 845 | 861 | |
muc/por d | 13 | 62 | 75 | |
UICC classification | 0.57 | |||
Stage 0- II | 15 | 411 | 426 | |
Stage III- IV | 14 | 496 | 510 | |
Type 2 diabetes mellitus | 0.0007 | |||
− | 28 | 633 | 661 | |
+ | 1 | 274 | 275 | |
Body mass index | 0.65 | |||
<25.00 kg/m2 | 21 | 698 | 719 | |
≧25.00 kg/m2 | 8 | 209 | 217 | |
KRAS gene | <0.0001 | |||
Wild type | 29 | 630 | 659 | |
Mutant type | 0 | 277 | 277 | |
BRAF gene | <0.0001 | |||
Wild type | 7 | 880 | 887 | |
Mutant type | 22 | 27 | 49 |
a Right: Cecum, Ascending colon, and Transverse colon
b Left: Descending colon, Sigmoid colon, Rectosigmoid colon, and Rectum
c wel: well differentiated adenocarcinoma; mod: moderately differentiated adenocarcinoma
d muc: mucinous carcinoma; por: poorly differentiated adenocarcinoma