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. 2019 Apr 19;14(4):e0215513. doi: 10.1371/journal.pone.0215513

Table 1. Clinicopathological characteristics of the patients.

Features MSI-H MSS Total P value
Total 29 907 936
Gender 0.022
   Male 10 514 524
   Female 19 393 412
Age (years old) 0.007
   ≦69 9 516 525
   ≧70 20 391 411
Location <0.0001
   Right a 24 220 244
   Left b 5 687 692
Histology <0.0001
   wel/mod c 16 845 861
   muc/por d 13 62 75
UICC classification 0.57
   Stage 0- II 15 411 426
   Stage III- IV 14 496 510
Type 2 diabetes mellitus 0.0007
   − 28 633 661
   + 1 274 275
Body mass index 0.65
   <25.00 kg/m2 21 698 719
   ≧25.00 kg/m2 8 209 217
KRAS gene <0.0001
   Wild type 29 630 659
   Mutant type 0 277 277
BRAF gene <0.0001
   Wild type 7 880 887
   Mutant type 22 27 49

a Right: Cecum, Ascending colon, and Transverse colon

b Left: Descending colon, Sigmoid colon, Rectosigmoid colon, and Rectum

c wel: well differentiated adenocarcinoma; mod: moderately differentiated adenocarcinoma

d muc: mucinous carcinoma; por: poorly differentiated adenocarcinoma