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. Author manuscript; available in PMC: 2019 Sep 18.
Published in final edited form as: Nat Immunol. 2019 Mar 18;20(5):602–612. doi: 10.1038/s41590-019-0342-0

Figure 8. T cells activated at the highest viral doses traffic rapidly to the infected tissue.

Figure 8.

a) Number of T cells in the ear at the indicated viral dose. (For no ear, only footpad infection was given. For no footpad, only ear infection was given). Dots show individual ears. n = 10 ears from 5 mice. b) Number of IFN-γ producing OT-I CD8+ T cells in the ear after infection with indicated viral dose. Note that for these experiments, mice were infected in the ear pinna with VACV expressing SIINFEKL 24 h after footpad infection. Dots show individual animals. n = 5 ears from 5 mice. Statistics = unpaired two-tailed t test. For a and b, results were repeated 3 times with 5 mice/group.