Table 2.
Characteristics of the Different Groups of Constipated Subjects According to Body Mass Index Group
| Variables | Total | BMI group (kg/m2) | P-value | ||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Underweight < 18.5 |
Normal 18.5–< 25 |
Overweight 25–< 30 |
Obesity 30–< 35 |
Morbid obesity ≥35 | |||
| Demographics | |||||||
| Number | 354 (100) | 13 (4) | 171 (48) | 113 (32) | 34 (10) | 23 (6) | |
| Age (yr) | 46.0 ± 15.9 | 38.9 ± 10.3 | 43.9 ± 16.7 | 48.6 ± 15.2 | 51.5 ± 14.2 | 44.9 ± 13.6 | 0.011 |
| Female gender | 297 (84) | 12 (92) | 151 (88) | 86 (76) | 27 (79) | 21 (91) | 0.047 |
| BMI (kg/m2) | 25.5 ± 5.5 | 17.2 ± 1.1 | 22.1 ± 1.8 | 26.7 ± 1.4 | 31.9 ± 1.5 | 40.0 ± 4.9 | |
| Clinical phenotype | |||||||
| Functional constipation | 215 (61) | 8 (4) | 93 (43) | 75 (35) | 19 (9) | 20 (9) | 0.023 |
| IBS-C | 139 (39) | 5 (4) | 78 (56) | 38 (27) | 15 (11) | 3 (2) | |
| Defecation disorders | 243 (69) | 10 (77) | 115 (67) | 77 (68) | 27 (79) | 14 (61) | 0.548 |
| Scales | |||||||
| LS-constipation | 6.0 ± 2.5 | 6.2 ± 2.4 | 6.0 ± 2.6 | 6.0 ± 2.6 | 6.2 ± 2.4 | 5.5 ± 1.8 | 0.886 |
| LS-bloating | 5.1 ± 2.9 | 4.9 ± 3.4 | 5.0 ± 3.0 | 5.5 ± 2.7 | 4.9 ± 3.0 | 4.5 ± 2.2 | 0.408 |
| LS-abdominal pain | 4.2 ± 2.9 | 6.0 ± 3.1 | 3.8 ± 3.0 | 4.7 ± 2.8 | 4.3 ± 3.1 | 3.0 ± 1.8 | 0.005 |
| Bristol stool form | 2.1 ± 1.3 | 2.4 ± 1.6 | 2.0 ± 1.3 | 2.2 ± 1.2 | 2.0 ± 1.4 | 2.1 ± 0.8 | 0.828 |
| CTT (hr) | |||||||
| Right CTT | 22.9 ± 21.5 | 22.9 ± 14.3 | 24.7 ± 20.7 | 22.5 ± 24.5 | 20.8 ± 20.9 | 15.0 ± 14.2 | 0.323 |
| Left CTT | 28.2 ± 22.4 | 19.7 ± 19.9 | 31.3 ± 23.0 | 24.6 ± 19.9 | 29.3 ± 23.6 | 25.7 ± 26.3 | 0.078 |
| RSTT | 17.9 ± 17.2 | 20.2 ± 19.2 | 21.4 ± 18.6 | 14.3 ± 15.4a | 15.7 ± 13.8 | 11.0 ± 12.2 | 0.002 |
| Total CTT | 69.9 ± 43.3 | 62.8 ± 40.3 | 79.5 ± 44.2 | 61.2 ± 41.9a | 65.8 ± 36.8 | 51.7 ± 39.5b | 0.001 |
a
P < 0.01 by comparison with patients with body mass index (BMI) in the normal range.
b
P < 0.05 by comparison with patients with BMI in the normal range.
P < 0.05 was considered significant.
IBS-C, irritable bowel syndrome with constipation; LS, Likert scale; CTT, colonic transit time; RSTT, rectosigmoid transit time.
Quantitative parameters are expressed as mean ± SD and qualitative parameters are shown as n (%).