Skip to main content
. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Biol Psychiatry. 2018 Nov 29;85(9):713–725. doi: 10.1016/j.biopsych.2018.11.010

Table 2.

Meta-analysis results for fMRI studies of error-processing and inhibitory control in OCD and HC.

Contrast MNI x, y, z Coordinates Peak SDM-Z Peak SMD Mean SMD P Value No. of Voxels Brodmann areas
Errors OCD > HC

R aI/fO 44,42,18 2.80 0.27 0.22 0.0005 302 45,44
R aLPFC 24,50,12 3.714 0.35 0.24 0.000005 123 10,46
L & R pre-SMA, R premotor cortex 20,12,48 2.797 0.26 0.21 0.0005 126 8
L & R dACC/SMA 4,10,46 2.527 0.25 0.21 0.001 111 32,24,6

Errors HC > OCD

L & R occipital lobe 10,−82,16 −2.630 −0.25 −0.17 0.00005 545 18,17,19
R MTL 50,−4,−20 −2.224 −0.21 −0.17 0.0005 97 21

Inhibitory control OCD > HC

L premotor cortex −26,0,60 2.5 0.23 0.16 0.00005 283 6
R premotor cortex 30,−6,52 2.349 0.22 0.15 0.00005 134 6
R ITL/occipital lobe 48,−54,−10 2.237 0.21 0.15 0.0001 102 37,19,20
R SPL 28,−52,56 2.096 0.19 0.14 0.0005 100 7

Inhibitory control HC > OCD

L & R thalamus, L caudate −16,6,22 −3.68 −0.34 −0.27 0.00005 437
L & R dACC/rACC/vACC 14,42,12 −3.789 −0.35 −0.27 0.00005 410 32,24,11,25
R occipital lobe 26,−54,2 −4.205 −0.4 −0.31 0.000005 310 19,17
R SMG/angular gyrus 56,−44,30 −3.483 −0.32 −0.25 0.0001 347 40,39
L occipital lobe/cerebellum −28,−46,−8 −2.813 −0.26 −0.24 0.005 135 37,18,19
R mOFC 20,36,−18 −3.514 −0.33 −0.26 0.0001 101 11
R caudate 18,−12,22 −3.399 −0.32 −0.27 0.0005 90
R aI/fO/STL 48,18,4 −3.131 −0.29 −0.25 0.0005 88 45,44,38

Abbreviations: ai, anterior insula; aLPFC, anterior lateral prefrontal cortex; dACC, dorsal anterior cingulate cortex; fO, frontal operculum; HC, healthy controls; ITL, inferior temporal lobe; IPL, inferior parietal lobe; mOFC, medial orbitofrontal cortex; MNI, Montreal Neurological Institute; MTL, middle temporal lobe; pre-SMA, pre-supplementary motor area; OCD, obsessive-compulsive disorder; rACC, rostral anterior cingulate cortex; SDM, a Seed-based d Mapping; SMD, standardized mean difference (Hedges’ g); SMA, supplementary motor area; SMG, supramarginal gyrus; SPL, superior parietal lobe; STL, superior temporal lobe; vACC, ventral anterior cingulate cortex.