Figure 1. Structure of chloramphenicol and its bacterial modifications.
Chemical structure of (A) chloramphenicol, (B) chloramphenicol inactivated following acetylation, and (C) chloramphenicol inactivated following nitro reduction. (D) Products of step-wise chloramphenicol reduction, from left to right: chloramphenicol, nitroso-chloramphenicol, hydroxylamine-chloramphenicol, and amino-chloramphenicol.