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. 2019 Apr 19;9:6316. doi: 10.1038/s41598-019-42838-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fenofibrate down-regulates ‘oncoproteins’ in MS1 VEGF angiosarcoma cells. Data were generated by western blotting in MS1 VEGF angiosarcoma cells. (a) Example experiments (horizontal bars) showing the effect of a 48-hour treatment with 50 μM fenofibrate (feno) on the expression of Bcl-2, survivin, Akt, ERK, Bcl-XL, α- tubulin and β-actin. (b) Mean data from 5–6 independent experiments for data exemplified in (a). β-actin was used as a normalization control. Dashed boxes indicate individual gels and boxed regions within correspond to different sections of the same gel. *P < 0.05; **P < 0.01; ****P < 0.0001; n.s., not significant (Student’s t-test).