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. 2019 Apr 19;9:6309. doi: 10.1038/s41598-019-42693-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Connectivity assessment using Global Efficiency measure. (a) Active tPBM caused significant changes in network global efficacy in the alpha band for 50–60%, 75%, 85–90% of sparsity levels, in the gamma band for 15%, 50–60%, 70–75% and 90% of sparsity levels. (b) Sham tPBM did not cause any significant change in the global efficacy. Blue and red lines line indicate pre and post conditions, respectively. The gray lines indicate a significant difference (P < 0.01) at a certain sparsity level.