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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Ann Surg Oncol. 2018 Jul 5;25(10):3019–3029. doi: 10.1245/s10434-018-6587-2

Table 2.

Adjusted Overall Survival Model (N=7,025).

HR (95% CI) P-Value Overall P-Value
Axillary Surgery Group <0.001
 SLNB (1–5 LNs) REF
 ALND (10+ LNs) 0.678 (0.556 – 0.828) <0.001
Age (Years) 1.011 (1.005 – 1.017) <0.001 <0.001
Race 0.002
 White REF
 Black 1.291 (1.108 – 1.505) 0.001
 Other 0.74 (0.48 – 1.141) 0.17
Charlson/Deyo Score <0.001
 0 REF
 1 1.329 (1.127 – 1.567) <.0001
 ≥2 1.561 (1.173 – 2.077) 0.002
Income Level 0.03
 ≥$35,000 REF
 <$35,000 1.176 (1.016 – 1.362) 0.03
Insurance Type <0.001
 Private REF
 Government 1.347 (1.17 – 1.551) <0.001
 Not Insured 1.303 (0.967 – 1.755) 0.08
Education Level 0.49
 >80% High School Graduation Rate REF
 ≤80% High School Graduation Rate 0.949 (0.818 – 1.1) 0.49
ER Status 0.25
 Positive 0.88 (0.706 – 1.096) 0.25
 Negative REF
PR Status <.001
 Positive 0.562 (0.472 – 0.669) <0.001
 Negative REF
HER2 Status* <0.001
 Positive 0.585 (0.499 – 0.686) <0.001
 Negative REF
Clinical N-Stage 0.08
 2 REF
 3 1.137 (0.984 – 1.314) 0.08
Clinical T-Stage <0.001
 1 REF
 2 1.222 (1.028 – 1.453) 0.02
 3 1.547 (1.276 – 1.875) <0.001
Grade <0.001
 1 REF
 2 1.02 (0.738 – 1.409) 0.91
 3 1.613 (1.168 – 2.228) 0.004
Histology 0.20
 Invasive Ductal REF
 Invasive Lobular 0.856 (0.684 – 1.072) 0.18
 Other Invasive 0.719 (0.433 – 1.193) 0.202
Surgery Type 0.002
 Mastectomy REF
 Lumpectomy 0.787 (0.675 – 0.916) 0.002
# Positive LNs 1.04 (1.031 −1.048) <0.001 <0.001
Chemotherapy Use 0.48 (0.404 – 0.571) <0.001 <0.001
Radiation Use 0.676 (0.586 – 0.779) <0.001 <0.001
Endocrine Therapy Use 0.637 (0.522 – 0.778) <0.001 <0.001
*

HER2 status is frequently missing in this database, hence the highly reduced sample size included in this model.