Table 2.
Adjusted Overall Survival Model (N=7,025).
HR (95% CI) | P-Value | Overall P-Value | |
---|---|---|---|
Axillary Surgery Group | <0.001 | ||
SLNB (1–5 LNs) | REF | ||
ALND (10+ LNs) | 0.678 (0.556 – 0.828) | <0.001 | |
Age (Years) | 1.011 (1.005 – 1.017) | <0.001 | <0.001 |
Race | 0.002 | ||
White | REF | ||
Black | 1.291 (1.108 – 1.505) | 0.001 | |
Other | 0.74 (0.48 – 1.141) | 0.17 | |
Charlson/Deyo Score | <0.001 | ||
0 | REF | ||
1 | 1.329 (1.127 – 1.567) | <.0001 | |
≥2 | 1.561 (1.173 – 2.077) | 0.002 | |
Income Level | 0.03 | ||
≥$35,000 | REF | ||
<$35,000 | 1.176 (1.016 – 1.362) | 0.03 | |
Insurance Type | <0.001 | ||
Private | REF | ||
Government | 1.347 (1.17 – 1.551) | <0.001 | |
Not Insured | 1.303 (0.967 – 1.755) | 0.08 | |
Education Level | 0.49 | ||
>80% High School Graduation Rate | REF | ||
≤80% High School Graduation Rate | 0.949 (0.818 – 1.1) | 0.49 | |
ER Status | 0.25 | ||
Positive | 0.88 (0.706 – 1.096) | 0.25 | |
Negative | REF | ||
PR Status | <.001 | ||
Positive | 0.562 (0.472 – 0.669) | <0.001 | |
Negative | REF | ||
HER2 Status* | <0.001 | ||
Positive | 0.585 (0.499 – 0.686) | <0.001 | |
Negative | REF | ||
Clinical N-Stage | 0.08 | ||
2 | REF | ||
3 | 1.137 (0.984 – 1.314) | 0.08 | |
Clinical T-Stage | <0.001 | ||
1 | REF | ||
2 | 1.222 (1.028 – 1.453) | 0.02 | |
3 | 1.547 (1.276 – 1.875) | <0.001 | |
Grade | <0.001 | ||
1 | REF | ||
2 | 1.02 (0.738 – 1.409) | 0.91 | |
3 | 1.613 (1.168 – 2.228) | 0.004 | |
Histology | 0.20 | ||
Invasive Ductal | REF | ||
Invasive Lobular | 0.856 (0.684 – 1.072) | 0.18 | |
Other Invasive | 0.719 (0.433 – 1.193) | 0.202 | |
Surgery Type | 0.002 | ||
Mastectomy | REF | ||
Lumpectomy | 0.787 (0.675 – 0.916) | 0.002 | |
# Positive LNs | 1.04 (1.031 −1.048) | <0.001 | <0.001 |
Chemotherapy Use | 0.48 (0.404 – 0.571) | <0.001 | <0.001 |
Radiation Use | 0.676 (0.586 – 0.779) | <0.001 | <0.001 |
Endocrine Therapy Use | 0.637 (0.522 – 0.778) | <0.001 | <0.001 |
HER2 status is frequently missing in this database, hence the highly reduced sample size included in this model.