Figure 4.

Association between estimated 2‐year major adverse cardiac event rate and anatomical and physiologic disease burden. SYNTAX score (A), residual SYNTAX score (B), and 3‐vessel FFR (C) showed significant association with the estimated 2‐year MACE rates in both sexes. There was no significant interaction of sex in the relationship between total disease burden and clinical outcomes. FFR indicates fractional flow reserve; HR, hazard ratio; MACE, major adverse cardiovascular events; SYNTAX, Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery.