Table 4.
Associations of Total Disease Burden for 2‐Year Major Adverse Cardiac Events According to Sex
| Variable | Total Population | Women | Men | P for Interaction | |||
|---|---|---|---|---|---|---|---|
| Adjusted HR (95% CI) | P Value | Adjusted HR (95% CI) | P Value | Adjusted HR (95% CI) | P Value | ||
| SYNTAX score (by 1 increase) | 1.067 (1.036‐1.098) | <0.001 | 1.160 (1.052‐1.278) | 0.003 | 1.054 (1.020‐1.089) | 0.002 | 0.078 |
| Residual SYNTAX score (by 1 increase) | 1.065 (1.031‐1.101) | <0.001 | 1.127 (1.018‐1.249) | 0.021 | 1.055 (1.018‐1.093) | 0.004 | 0.191 |
| 3‐vessel FFR (by 0.1 decrease) | 1.346 (1.146‐1.579) | <0.001 | 2.315 (1.237‐4.332) | 0.009 | 1.292 (1.090‐1.531) | 0.003 | 0.155 |
| Functional SYNTAX score (by 1 increase) | 1.066 (1.031‐1.102) | <0.001 | 1.095 (0.993‐1.208) | 0.070 | 1.059 (1.021‐1.099) | 0.002 | 0.309 |
Multivariable Cox regression analysis adjusted with age, hypertension, diabetes mellitus, hyperlipidemia, current smoking, acute coronary syndrome, and previous myocardial infarction. FFR indicates fractional flow reserve; HR, hazard ratio; SYNTAX, Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery.