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. 2018 Oct 3;7(20):e010224. doi: 10.1161/JAHA.118.010224

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© 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Additional representative case 1. CCTA revealed heavy coronary calcification and obstructive stenosis (≥70%) in the distal portion of the right coronary artery (CCTA, arrowhead). The fused PET/CT images showed enhanced ¹⁸F‐sodium fluoride (¹⁸F‐NaF) uptake corresponding to the calcification (maximum tissue‐to‐background ratio=1.6) (¹⁸F‐NaF PET/CT, arrows). This patient experienced unstable angina resulting from subtotal occlusion in the lesion corresponding to the calcification (invasive coronary angiography, arrow) 1 month after ¹⁸F‐NaF PET/CT scan. CCTA indicates coronary computed tomography angiography; CT, computed tomography; PET, positron emission tomography.