Table 4.

Incidence of Aortic and Mitral Valve Replacement or Repair Surgery and Pacemaker Insertions in Men and Women With ASp and Control Group Without ASp, by Age Group

	Number of Events		Incidence (per 100 000 Patient‐Years)a		Relative Risk (95% CI)a
	ASp	Control	ASp	Control
Aortic valve procedures
Men
Age 65–69 y	84	29 527	150	113	1.33 (1.07, 1.65)
Age 70–74 y	132	45 511	212	182	1.16 (0.98, 1.38)
Age 75–79 y	173	52 466	295	256	1.15 (0.99, 1.34)
Age 80 y or older	224	64 017	311	256	1.21 (1.06, 1.39)
Women
Age 65–69 y	22	9289	77	60	1.27 (0.83, 1.94)
Age 70–74 y	40	15 070	126	97	1.29 (0.95, 1.77)
Age 75–79 y	68	19 660	202	139	1.45 (1.14, 1.84)
Age 80 y or older	140	28 665	240	121	1.98 (1.67, 2.34)
Mitral valve surgery
Men
Age 65–69 y	32	12 823	57	49	1.17 (0.82, 1.66)
Age 70–74 y	49	17 335	78	69	1.13 (0.85, 1.50)
Age 75–79 y	51	17 885	86	87	1.00 (0.75, 1.32)
Age 80 y or older	49	15 206	67	60	1.12 (0.84, 1.48)
Women
Age 65–69 y	14	6439	49	42	1.16 (0.69, 1.98)
Age 70–74 y	20	9125	63	59	1.07 (0.69, 1.67)
Age 75–79 y	16	9952	47	70	0.68 (0.41, 1.11)
Age 80 y or older	23	8891	39	37	1.04 (0.69, 1.58)
Pacemaker insertion
Men
Age 65–69 y	234	84 312	426	327	1.30 (1.14, 1.48)
Age 70–74 y	487	144 949	807	596	1.35 (1.23, 1.49)
Age 75–79 y	662	190 474	1192	971	1.22 (1.13, 1.33)
Age 80 y or older	1185	378 401	1823	1648	1.10 (1.04, 1.18)
Women
Age 65–69 y	65	29 070	229	190	1.20 (0.94, 1.54)
Age 70–74 y	125	54 242	399	354	1.13 (0.94, 1.35)
Age 75–79 y	224	80 901	685	585	1.17 (1.02, 1.34)
Age 80 y or older	573	216 906	1035	964	1.07 (0.98, 1.17)

ASp indicates ankylosing spondylitis; CI, confidence interval.

^aRace‐standardized to the composition of the control group in each age‐sex group.