Table 4.
SNPs Associated With AF From GWASs
| SNP | Locus | Gene | Location Relative to Closest Gene | References |
|---|---|---|---|---|
| rs6666258 | 1q21 | KCNN3‐PMVK | Intronic | 105 |
| rs6817105 | 4q25 | PITX2 | 150 kb Upstream | 105 |
| rs3903239 | 1q24 | PRRX1 | 46 kb Upstream | 106 |
| rs2040862 | 5q31 | WNT8A | Intronic | 105 |
| rs3807989 | 7q31 | CAV1 | Intronic | 107, 108 |
| rs10821415 | 9q22 | C9orf3 | Intronic | 109 |
| rs10824026 | 10q22 | SYNPO2L | 5 kb Upstream | 110 |
| rs1152591 | 14q23 | SYNE2 | Intronic | 111 |
| rs7164883 | 15q24 | HCN4 | Intronic | 37 |
| rs2106261 | 16q22 | ZFHX3 | Intronic | 105 |
| rs4642101 | 3p25 | CAND2 | Intronic | 112 |
| rs13216675 | 6p22 | GJA1 | Intergenic | 62 |
| rs12415501 | 10q24 | NEURL | Intronic | 112 |
| rs6584555 | 10q24 | NEURL | Intronic | 112 |
| rs10507248 | 12q24 | TBX5 | Intronic | 55 |
| rs6490029 | 12q24 | CUX2 | Intronic | 114 |
| rs72700118 | 1q24 | METTL11B/KIFAP3 | Intergenic | 115 |
| rs3771537 | 2p13 | ANXA4/GMCL1 | Intronic | 115 |
| rs2540949 | 2p14 | CEP68 | Intronic | 115 |
| rs2288327 | 2q31 | TTN/TTN‐AS1 | Intronic | 115 |
| rs337711 | 5q22 | KCNN2 | Intronic | 115 |
| rs2967791 | 5q31 | KLHL3/WNT8A/FAM13B | Intronic | 115 |
| rs4946333 | 6q22 | SLC35F1/PLN | Intronic | 115 |
| rs7508 | 8p22 | ASAH1/PCM1 | 3′UTR | 115 |
| rs35176054 | 10q24 | SH3PXD2A | Intronic | 115 |
| rs75190942 | 11q24 | KCNJ5 | Intronic | 115 |
| rs6800541 | 3p22 | SCN10A (EWAS) | Intronic | 115 |
| rs89107 | 6q22 | SLC35F1/PLN (EWAS) | Intronic | 115 |
| rs11047543 | 12p12 | SOX5 (EWAS) | Intergenic | 115 |
AF indicates atrial fibrillation; EWAS, exome‐wide association study; GWAS, genome‐wide association study; SNP, single‐nucleotide polymorphism; UTR, untranslated region.