Table 2.
Profibrotic Gene Transcripts
| Gene | Cardiomyocytes | Fibroblasts | ||||
|---|---|---|---|---|---|---|
| Fold Change | SD | P Value | Fold Change | SD | P Value | |
| Acta2 | 1.504 | 0.373 | 0.512 | 1.127 | 0.208 | 0.781 |
| Ctgf | 11.590 | 3.884 | 0.023 | 44.797 | 11.322 | 0.033 |
| Col1a2 | 12.688 | 4.771 | 0.036 | 21.698 | 5.612 | 0.041 |
| Col3a1 | 10.202 | 3.963 | 0.035 | 52.169 | 23.548 | 0.156 |
| Tgfb1 | 2.757 | 0.373 | 0.326 | 2.429 | 0.748 | 0.261 |
| Tgfb2 | 4.525 | 1.699 | 0.219 | 19.540 | 6.669 | 0.042 |
| Tgfb3 | 3.421 | 1.741 | 0.381 | 25.992 | 8.323 | 0.031 |
Data from quantitative PCR measuring profibrotic genes at 3 months using isolated cardiomyocytes and fibroblasts from nontransgenic (Ntg) and mutant αB‐crystallin CryABR120G mice (n=6). Fold induction is expressed as mean±SD.