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. 2018 Oct 11;7(20):e009775. doi: 10.1161/JAHA.118.009775

Figure 1.

Figure 1

Cardiac hemodynamics in the Wt and Sigmar1−/− heart. Cardiovascular performance in anesthetized, closed‐chest mice under baseline conditions. A, Heart rate (beats/min). B, Maximal LV pressure (LVP). C, Systolic blood pressure. D, Mean arterial blood pressure (MAP). E, Maximum rate of LV contraction (dp/dtmax). F, Maximum rate of LV relaxation (dP/dtmin). G, LV end‐diastolic pressure (LVEDP). H, Relaxation time constant (τ). All measurements were carried out using 3‐ to 4‐month‐old Sigmar1−/− mice with littermate Wt mice used as controls (n=4 to 5 mice per group). Boxes represent interquartile ranges, lines represent medians, whiskers represent ranges, and P values were determined by Kruskal‐Wallis test. LV indicates left ventricle; NS, not significant; Wt, wild type.