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. 2019 Mar 12;8(6):e011139. doi: 10.1161/JAHA.118.011139

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© 2019 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Kaplan–Meier event rate curves for the cumulative incidence of (A) major bleeding, and (B) non‐CABG‐related major bleeding stratified by DM/CKD status. P value represents the overall comparison among groups according to DM/CKD status. Bleeding is defined according to PLATO criteria. The model is adjusted for age, sex, body mass index, heart rate, prior myocardial infarction, hypertension, dyslipidemia, angina pectoris, smoking status, previous percutaneous coronary intervention, or coronary artery bypass graft, type of acute coronary syndrome, and randomized treatment. CABG indicates coronary artery bypass graft; CKD, chronic kidney disease; DM, diabetes mellitus; PLATO, Platelet Inhibition and Patient Outcomes.