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. Author manuscript; available in PMC: 2019 Apr 20.
Published in final edited form as: Dig Liver Dis. 2016 Nov 17;49(2):188–196. doi: 10.1016/j.dld.2016.11.008

Figure 5: Biodistribution study relative to liver, kidney, and spleen demonstrated significant uptake of the siRNA FITC-loaded NP while mice received HFD.

Figure 5:

Histology after tail veins intravenous injections of FITC tagged siRNA-loaded NPs (5mg/mL, 100μL) (green), mice were sacrificed and (A, D) kidney, (B, E) spleen, and (C, F) liver samples were stained for Alexa Fluor 568 phalloidin (red) and DAPI (blue). Mice were fed a high fat diet for 8 weeks along with biweekly tail vein intravenous injections of FITC-loaded NPs (5mg/mL, 100μL). Scale bar is 50 μm.