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. Author manuscript; available in PMC: 2019 Apr 20.
Published in final edited form as: Dig Liver Dis. 2016 Nov 17;49(2):188–196. doi: 10.1016/j.dld.2016.11.008

Figure 6: Flow cytometry analysis indicating that biweekly injection of CD98 siRNA-loaded NPs is significantly uptake by hepatocytes and macrophage-like cells compared to dendritic cells.

Figure 6:

Representative FACS plots illustrating the gating strategy utilized to define live cells (A), macrophages like cells (B), dendritic cells (C) and hepatocytes (D) for mice biweekly injected with FITC-loaded NPs (5mg/mL, 100μL) and receiving or not HFD. Cells were gated as followed for hepatocytes CD45-MHC class II−F4/80−CD11b-CD11c-albumin+, macrophages-like cells CD45+MHC class II+F4/80+CD11b+CD11c- cells and dendritic cells CD45+MHC class II+ F4/80−CD11b+CD11c+. Values represent means ± SE. Data are representative of n=5 mice per group. **P < 0.01, *P < 0.05 and NS, not statically significant.