Table 1.

Single letter code of 12 peptides (red dash line indicates expected cleavage site), critical aggregation concentrations of peptides determined using pyrene (Figure S9 in SI), and zeta potentials of 5 mM peptides in 2% PBS (pH 7.4) at 25°C (Figure S8 in SI).

Peptide Sequence												Charge	CAC*	Zeta Potential
Position	P6	P5	P4	P3	P2	P1	P1’	P2’	P3’	P4’	P5’	pH 7.4	(mM)	Mean (mV) ± Std. dev
				P/A	X1	G	L	X2	G
1AK		F	F	A	L	G	L	A	G	K	K	+2	0.4	11.5 ± 0.8
1AD		F	F	A	L	G	L	A	G	D	D	−2	0.6	−34.9 ± 1.1
1PK		F	F	P	L	G	L	A	G	K	K	+2	0.3	15.4 ± 0.3
1PD		F	F	P	L	G	L	A	G	D	D	−2	0.5	−38.0 ± 1.7
2AK	F	F	G	A	L	G	L	K	G	K		+2	0.4	8.2 ± 2.8
2AD	F	F	G	A	L	G	L	D	G	D		−2	0.6	−30.3 ± 1.4
2PK	F	F	G	P	L	G	L	K	G	K		+2	0.3	4.1 ± 1.0
2PD	F	F	G	P	L	G	L	D	G	D		−2	0.7	−41.2 ± 2.3
3AK	F	F	G	A	A	G	L	K	G	K		+2	0.8	1.3 ± 0.6
3AD	F	F	G	A	A	G	L	D	G	D		−2	0.5	−7.5 ± 1.8
3PK	F	F	G	P	A	G	L	K	G	K		+2	0.7	1.1 ± 1.5
3PD	F	F	G	P	A	G	L	D	G	D		−2	0.5	−28.2 ± 0.7

^*CAC: critical aggregation concentration