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. 2018 Nov 2;74(5):500–502. doi: 10.1136/thoraxjnl-2018-211851

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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Longitudinal change in FVC, D_LCO and RBC:TP. (A–C): Box and whisker diagrams with associated Friedman’s test p values, representing 6-month and 12-month follow-up change in FVC, D_LCO and 129-xenon MR-derived RBC:TP ratio. Note that a statistically significant difference was not demonstrated in D_LCO (B), whereas FVC (A) and RBC:TP (C) declined significantly over 12 months. Individual participants’ metrics of FVC, D_LCO and RBC:TP at baseline, 6 and 12 months are plotted in (D), (E) and (F), respectively. D_LCO, diffusing capacity of the lungs for carbon monoxide; FVC, forced vital capacity; RBC:TP, red blood cell to tissue/plasma.