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. 2018 Nov 26;74(4):380–389. doi: 10.1136/thoraxjnl-2018-212144

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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Prognostic HDL subclasses. (A) HRs and 95% CI after correcting for age, diuretic treatment and the presence of atrial fibrillation/flutter are shown for all HDL subclasses in the discovery and validation cohorts. Red/yellow indicates HDL subclasses, which meet Bonferroni correction in both cohorts. (B) Average composition of the HDL-4 subclass is shown across patients with PAH. Apo, apolipoprotein; CI, confidence interval; HDL, high-density lipoprotein; HR, hazard ratio; PAH, pulmonary arterial hypertension.