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. Author manuscript; available in PMC: 2019 Sep 21.
Published in final edited form as: ACS Chem Biol. 2018 Aug 30;13(9):2794–2807. doi: 10.1021/acschembio.8b00729

Figure 6.

Figure 6.

Mass-spectrometry characterization of WT and G93A-SOD1. Each protein was incubated in the presence of 0.25 M DTT for 10 min at RT and then subjected to LC-MS analysis. (A) Recorded (top) and deconvoluted (bottom) spectra of WT SOD1. (B) Recorded (top) and deconvoluted (bottom) spectra of G93A-SOD1. The fragmentation type (A, B, or C) and charge of each fragment is indicated in red and the observed mass in black.