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. 2019 Mar 20;9(3):e019186. doi: 10.1136/bmjopen-2017-019186

Table 4.

Prevalence of PIMs and PPOs identified by POPI in hospital

Criteria No. of PIMs No. of patients with the targeted disorders* % of PIMs in patients with the targeted disorders
PIMs 541 7304 7.4%
Various illnesses 3 64 4.6%
  AI-6 Opiates to treat migraine attacks 3 64 4.6%
Digestive disorders 56 1956 2.8%
  EI-2 Domperidone 28 1956 1.4%
  FI-3 The use of diosmectite (Smecta) in combination with another medication. 27 1956 1.4%
  EI-1 Metoclopramide 1 1956 <0.1%
ENT-Pulmonary disorders 472 5163 9.1%
  II-4 Antibiotics to treat acute suppurative otitis media and so on. 2 7 28.6%
  II-2 Antibiotic treatment for a sore throat, without a positive RDT. 23 160 14.4%
  II-9 Ear drops in the event of acute otitis media. 86 1083 7.9%
  HI-1 Beta2 agonist, corticosteroids to treat an infant’s first case of bronchiolitis. 25 386 6.4%
  II-5 Corticosteroids to treat acute suppurative otitis media and so on. 190 3616 5.2%
  II-1 An antibiotic other than amoxicillin as a first-line treatment. 59 1259 4.7%
  JI-1 H1-antagonist to treat asthma. 9 802 1.1%
  II-8 Tenoate etanolamine (Rhinotrophyl) and other nasal antiseptics. 21 2455 0.8%
  II-3 Antibiotics for nasopharyngitis. 26 3444 0.7%
  GI-3 Alimemazine (Theralene), oxomemezine (Toplexil) and so on. 18 2585 0.7%
  JI-2 Cough suppressants to treat asthma. 5 802 0.6%
  HI-2 H1-antagonists, cough suppressants and so on to treat bronchiolitis. 2 386 0.5%
  II-7 H1-antagonists with sedative or atropine-like effects. 4 2585 0.2%
  GI-2 Mucolytics drugs, mucokinetics drugs or helicidine before 2 years of age. 1 2585 <0.1%
  II-6 Nasal or oral decongestant and so on. 1 2455 <0.1%
Dermatological disorders 10 100 10%
  OI-1 A combination of locally applied and orally administered antibiotics. 9 32 28.1%
  PI-2 Topical agents containing acyclovir administered to a child under 6 years of age. 1 68 1.5%
No. of PPO No. of patients with the targeted disorders* % of PPOs in patients with the targeted disorders
PPOs 424 4508 9.4%
Digestive disorders 372 1956 19.0%
  EO-1 Oral rehydration solution in the event of vomiting. 135 313 43.1%
  FO-1 Oral rehydration solution in the event of diarrhoea. 237 1643 14.4%
ENT-Pulmonary disorders 51 1469 3.5%
  HO-1 0.9% NaCl to relieve nasal congestion and so on. 38 386 9.8%
  IO-2 Acetaminophen combined with antibiotic treatment for ear infections and so on. 13 1083 1.3%
Dermatological disorders 1 3 33.3%
  NO-2 Griseofulvin taken during a meal containing a moderate amount of fat. 1 3 33.3%

*The number of patients with the targeted disorder corresponds to patients with clinical situations at risk of PIM or PPO.

%, Percentage calculated by the number of PIMs or PPO detected from the total number of analyzable cases; ENT, ear, nose and throat; PIMs, potentially inappropriate medicines; PPOs, potentially prescribing omissions; RDT, rapid diagnostic test.