Table 1.
Demographic comparison between primary angle-closure glaucoma (PACG) cases and controls
| PACG cases n=3322 |
Controls n=13 288 |
P value | |||
| n | (%) | n | (%) | ||
| Sex | 0.999 | ||||
| Female | 2031 | 61.1 | 8124 | 61.1 | |
| Male | 5164 | 38.9 | 1291 | 38.9 | |
| Age group (years) | 0.999 | ||||
| 20–49 | 398 | 12.0 | 1592 | 12.0 | |
| 50–64 | 1011 | 30.4 | 4044 | 30.4 | |
| ≥65 | 1913 | 57.6 | 7652 | 57.6 | |
| Age (year), mean (SD)* | 65.2 (12.7) | 64.8 (13.0) | 0.100 | ||
| Comorbidity | |||||
| Hypertension | 2025 | 60.6 | 6896 | 51.9 | <0.001 |
| Ischaemic heart disease | 1097 | 33.0 | 3561 | 26.8 | <0.001 |
| Hyperlipidaemia | 1389 | 41.8 | 4399 | 33.1 | <0.001 |
| Congestive heart failure | 213 | 6.41 | 849 | 6.39 | 0.962 |
| Cardiac arrhythmias | 540 | 16.3 | 1826 | 13.7 | <0.001 |
| Peripheral vascular disorders | 201 | 6.05 | 571 | 4.30 | <0.001 |
| Stroke | 246 | 7.41 | 994 | 7.48 | 0.883 |
| Headaches | 1407 | 42.4 | 4772 | 35.9 | <0.001 |
| Migraine | 125 | 3.76 | 456 | 3.43 | 0.353 |
| Epilepsy | 30 | 0.90 | 144 | 1.08 | 0.360 |
| Dementia | 110 | 3.31 | 448 | 3.37 | 0.863 |
| Rheumatoid arthritis | 11 | 0.33 | 45 | 0.34 | 0.957 |
| Systemic lupus erythematosus | 3 | 0.09 | 8 | 0.06 | 0.546 |
| Chronic obstructive pulmonary disease | 675 | 20.3 | 2343 | 17.6 | <0.001 |
| Asthma | 418 | 12.6 | 1455 | 11.0 | 0.008 |
| Pulmonary circulation disorders | 26 | 0.78 | 85 | 0.64 | 0.366 |
| Diabetes | 710 | 21.4 | 2148 | 16.2 | <0.001 |
| Hypothyroidism | 36 | 1.08 | 110 | 0.83 | 0.158 |
| Renal failure | 448 | 13.5 | 1435 | 10.8 | <0.001 |
| Liver diseases | 898 | 27.0 | 2775 | 20.9 | <0.001 |
| Peptic ulcers | 1409 | 42.4 | 4503 | 33.9 | <0.001 |
| Hepatitis B | 182 | 5.48 | 610 | 4.59 | 0.032 |
| Tuberculosis | 86 | 2.59 | 294 | 2.21 | 0.194 |
| Deficiency anaemia | 114 | 3.43 | 381 | 2.87 | 0.087 |
| Depression | 328 | 9.87 | 922 | 6.94 | <0.001 |
| Psychosis | 153 | 4.61 | 518 | 3.90 | 0.064 |
| Metastatic cancer | 1 | 0.03 | 2 | 0.02 | 0.564 |
| Solid tumour | 190 | 5.72 | 630 | 4.74 | 0.020 |
| Cataract | 2088 | 62.9 | 4077 | 30.7 | <0.001 |
Data are presented as the number of subjects in each group, with percentages given in parentheses.
χ2 test; *t-test.