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. 2019 Mar 23;9(3):e024209. doi: 10.1136/bmjopen-2018-024209

Table 2.

Factors associated with risk of primary angle-closure glaucoma

Variable Crude Adjusted†
OR (95% CI) OR (95% CI)
Comorbidity
Hypertension 1.45 (1.34 to 1.56)*** 0.97 (0.88 to 1.07)
Ischaemic heart disease 1.35 (1.24 to 1.46)*** 0.92 (0.83 to 1.01)
Hyperlipidaemia 1.45 (1.34 to 1.57)*** 1.11 (1.01 to 1.21)*
Congestive heart failure 1.00 (0.86 to 1.17)
Cardiac arrhythmias 1.22 (1.10 to 1.35)*** 0.91 (0.81 to 1.02)
Peripheral vascular disorders 1.44 (1.22 to 1.69)*** 1.02 (0.86 to 1.21)
Stroke 0.98 (0.86 to 1.14)
Headaches 1.31 (1.21 to 1.42)*** 1.13 (1.04 to 1.23)***
Migraine 1.10 (0.90 to 1.35)
Epilepsy 0.83 (0.56 to 1.24)
Dementia 0.98 (0.79 to 1.21)
Rheumatoid arthritis 0.98 (0.51 to 1.89)
Systemic lupus erythematosus 1.50 (0.40 to 5.66)
Chronic obstructive pulmonary disease 1.19 (1.08 to 1.31)*** 0.88 (0.79 to 1.00)
Asthma 1.17 (1.04 to 1.32)*** 0.98 (0.86 to 1.11)
Pulmonary circulation disorders 1.23 (0.79 to 1.90)
Diabetes 1.41 (1.28 to 1.55)*** 1.03 (0.93 to 1.15)
Hypothyroidism 1.31 (0.90 to 1.92)
Renal failure 1.29 (1.15 to 1.44)*** 0.93 (0.82 to 1.05)
Liver diseases 1.40 (1.29 to 1.53)*** 1.14 (1.03 to 1.25)*
Peptic ulcers 1.44 (1.33 to 1.55)*** 1.10 (1.01 to 1.20)*
Hepatitis B 1.21 (1.02 to 1.43)* 1.09 (0.91 to 1.31)
Tuberculosis 1.18 (0.92 to 1.50)
Deficiency anaemia 1.20 (0.97 to 1.49)
Depression 1.47 (1.29 to 1.68)*** 1.12 (0.98 to 1.29)
Psychosis 1.19 (0.99 to 1.43)
Metastatic cancer 2.01 (0.18 to 22.1)
Solid tumour 1.22 (1.03 to 1.44)* 1.01 (0.85 to 1.20)
Cataract 3.82 (3.53 to 4.14)*** 3.80 (3.49 to 4.14)***

*p<0.05; **p<0.01; ***p<0.001.

†Covariables which were significantly associated with risk of PACG in univariable unconditional logistic regression model were further analysed by multivariable unconditional logistic regression model.