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. 2019 Mar 30;9(3):e026854. doi: 10.1136/bmjopen-2018-026854

Table 2.

Association between physical activity and NAFLD in male

Variable Case Control Univariate model Multivariate model 1 Multivariate model 2 Multivariate model 3
(MET-min/week) No  (%) No (%) OR (95% CI) aOR (95% CI) aOR (95% CI) aOR (95% CI)
Total amount of physical activity
 ≤1440 153 (41.2) 124 (33.4) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
 1440–3180 104 (28.0) 124 (33.4) 0.68 (0.48 to 0.97) 0.62 (0.41 to 0.93)* 0.62 (0.41 to 0.93)* 0.62 (0.41 to 0.92)*
 >3180 114 (30.7) 123 (33.2) 0.75 (0.53 to 1.06) 0.62 (0.41 to 0.92)* 0.61 (0.41 to 0.92)* 0.60 (0.40 to 0.91)*
P value for trend 0.09 0.02* 0.02* 0.01*
Light-intensity physical activity
 ≤525 121 (32.6) 125 (33.7) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
 525–1500 127 (34.2) 125 (33.7) 1.05 (0.74 to 1.49) 1.00 (0.67 to 1.49) 1.00 (0.67 to 1.50) 1.03 (0.69 to 1.55)
 >1500 123 (33.2) 121 (32.6) 1.05 (0.74 to 1.50) 0.96 (0.64 to 1.43) 0.96 (0.64 to 1.44) 0.95 (0.63 to 1.44)
P value for trend 0.79 0.83 0.84 0.82
Moderate-intensity physical activity
 None 204 (55) 170 (45.8) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
 ≤684 74 (19.9) 79 (21.3) 0.78 (0.54 to 1.14) 0.79 (0.52 to 1.21) 0.79 (0.51 to 1.21) 0.78 (0.51 to 1.20)
 >684 93 (25.1) 122 (32.9) 0.64 (0.45 to 0.89)* 0.59 (0.40 to 0.86)* 0.58 (0.39 to 0.86)* 0.58 (0.40 to 0.86)*
P value for trend 0.01* 0.01* 0.01* 0.01*
Vigorous-intensity physical activity
 None 272 (73.3) 251 (67.7) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
 ≤960 28 (7.5) 35 (9.4) 0.74 (0.44 to 1.25) 0.77 (0.42 to 1.42) 0.77 (0.42 to 1.42) 0.77 (0.42 to 1.41)
 >960 71 (19.1) 85 (22.9) 0.77 (0.54 to 1.10) 0.65 (0.43 to 0.98)* 0.65 (0.43 to 0.98)* 0.63 (0.41 to 0.95)*
P value for trend 0.12 0.03* 0.03* 0.02*

Multivariate model 1: adjusted for BMI, hypertension, diabetes and fasting blood glucose.

Multivariate model 2: adjusted for BMI, hypertension, diabetes, fasting blood glucose and sedentary time.

Multivariate model 3: adjusted for BMI, hypertension, diabetes, fasting blood glucose, sedentary time and energy intake.

aOR, adjusted OR; BMI, body mass index; MET, metabolic equivalent of energy; NAFLD, non-alcoholic fatty liver disease.

*P<0.05.