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. 2019 Mar 20;9(3):e023213. doi: 10.1136/bmjopen-2018-023213

Table 3.

Rate of hospitalisation for selected child outcomes and smoking status at first booking for respiratory infections, asthma and bronchiolitis for (A) the whole period of follow-up; and for two separate periods of follow-up: (B) from birth to first birthday and (C) from first birthday to fifth birthday

(A) Follow-up from birth to fifth birthday
Smoking status at first booking Infants at risk (N) Acute upper and lower respiratory infections Asthma Bronchiolitis
N Column % Row % N Column % Row % N Column % Row %
697 003 56 615 100.0 8.1 7549 100.0 1.1 24 088 100.0 3.5
Never smoked 391 861 30 549 54.0 7.8 3678 48.7 0.9 11 354 47.1 2.9
Current smoker 159 819 14 945 26.4 9.4 2412 32.0 1.5 7939 33.0 5.0
Former smoker 59 326 4966 8.8 8.4 654 8.7 1.1 1821 7.6 3.1
Unknown/missing 85 997 6155 10.9 7.2 805 10.7 0.9 2974 12.3 3.5
(B) Follow-up from birth to first birthday PAF (%)
Acute upper and lower respiratory infections Admission for specified outcome Infants at risk (N) Crude HR Adjusted* HR
N Column % Row %
18 541 100.0 2.7 697 003 HR (95% CI) HR (95% CI)
Never smoked 9573 51.6 2.4 391 861 1.00 (reference) 1.00 (reference) 6.7
Current smoker 5537 29.9 3.5 159 819 1.43 (1.38 to 1.48) 1.29 (1.25 to 1.34)
Former smoker 1484 8.0 2.5 59 326 1.02 (0.97 to 1.08) 0.97 (0.92 to 1.03)
Unknown/missing 1947 10.5 2.3 85 997 0.93 (0.89 to 0.98) 0.89 (0.84 to 0.93)
Asthma 606 100.0 0.1 697 003
Never smoked 242 39.9 0.1 391 861 1.00 (reference) 1.00 (reference) 21.9
Current smoker 248 40.9 0.2 159 819 2.51 (2.10 to 3.00) 2.15 (1.80 to 2.57)
Former smoker 46 7.6 0.1 59 326 1.25 (0.91 to 1.72) 1.18 (0.86 to 1.62)
Unknown/missing 70 11.6 0.1 85 997 1.33 (1.02 to 1.73) 1.29 (0.99 to 1.69)
Bronchiolitis 20 399 100.0 2.9 697 003
Never smoked 9499 46.6 2.4 391 861 1.00 (reference) 1.00 (reference) 10.1
Current smoker 6861 33.6 4.3 159 819 1.79 (1.73 to 1.84) 1.43 (1.38 to 1.48)
Former smoker 1534 7.5 2.6 59 326 1.07 (1.01 to 1.13) 1.03 (0.97 to 1.08)
Unknown/missing 2505 12.3 2.9 85 997 1.21 (1.16 to 1.27) 1.15 (1.09 to 1.21)
(C) Follow-up from first birthday to fifth birthday PAF (%)
Acute upper and lower respiratory infections Admission for specified outcome Infants at risk (N)† Crude HR Adjusted* HR
N Column % Row %
38 074 100.0 5.7 662 454 HR (95%  CI) HR (95%  CI)
Never smoked 20 976 55.1 5.6 373 436 1.00 (reference) 1.00 (reference) −0.2
Current smoker 9408 24.7 6.2 151 010 1.09 (1.07 to 1.12) 0.99 (0.97 to 1.02)
Former smoker 3482 9.1 6.1 56 645 1.09 (1.06 to 1.13) 1.04 (1.00 to 1.08)
Unknown/missing 4208 11.1 5.2 81 363 0.95 (0.92 to 0.98) 0.90 (0.87 to 0.94)
Asthma 6943 100.0 1.0 679 588
Never smoked 3436 49.5 0.9 382 327 1.00 (reference) 1.00 (reference) 7.1
Current smoker 2164 31.2 1.4 156 123 1.51 (1.43 to 1.59) 1.29 (1.22 to 1.37)
Former smoker 608 8.8 1.0 58 025 1.16 (1.07 to 1.27) 1.10 (1.00 to 1.20)
Unknown/missing 735 10.6 0.9 83 113 1.04 (0.96 to 1.12) 1.01 (0.92 to 1.10)
Bronchiolitis 3689 100.0 0.6 660 119
Never smoked 1855 50.3 0.5 373 219 1.00 (reference) 1.00 (reference) 4.0
Current smoker 1078 29.2 0.7 149 609 1.45 (1.34 to 1.56) 1.16 (1.08 to 1.25)
Former smoker 287 7.8 0.5 56 561 1.02 (0.90 to 1.15) 0.98 (0.87 to 1.11)
Unknown/missing 469 12.7 0.6 80 730 1.18 (1.06 to 1.30) 1.11 (1.01 to 1.24)

*Adjusted for: maternal age; infant gender, SIMD; mothers socioeconomic status; fathers socioeconomic status; parity; mode of delivery, infant feeding at 6–8 weeks and country of birth.

†The number of infants at risk from their first birthday to fifth birthday is the total number of infants aged 0–1 year (697 003) minus the specific outcome cases and any deaths or migration from 0–1 year.

PAF, population attributable fraction; SIMD, Scottish Index of Multiple Deprivation.