Table 1.

Definition of MCI by EADC in 2005 and the instruments and cut-offs used for its assessment in the study

MCI definition criteria	Instrument used	Assessment cut-off adopted in the study
1. Cognitive complaints coming from the patients or their families 2. Reporting of a relative decline in cognitive functioning during the past year by the patient or informant	History from the patient or bystander
3. Cognitive disorders as evidenced by clinical evaluation	Malayalam version of Addenbrooke’s Cognitive Examination (m-ACE).47	Score below the cut-off in at least one of the seven cognitive domains assessed. [One SD below the mean score (of that educational category) was taken as the cut-off for each domain]
4. Absence of major repercussions on daily life	Everyday Ability Scale for India (EASI)	95th percentile of EASI scores of subjects with no subjective or objective cognitive decline in the study sample was taken as cut-off. This was 2; a score up to 2 was taken as normal activities of daily living.
5. Absence of dementia	DSM IV criteria	Patients not satisfying this criteria

DSM-IV, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition; EADC, European Alzheimer’s Disease Consortium; MCI, mild cognitive impairment.