Table 6.
Model results
Risk group | Outcomes before application of either prevention scenario (baseline) | Scenario 1 (risk-based prevention) | Scenario 2 (risk-based plus screening-based prevention) | |||
Number of women in risk group | Early onset GBS (EOGBS) cases | Antibiotic type offered | Number of women receiving antibiotics | Antibiotic type offered | Number of women receiving antibiotics | |
Neonate affected by EOGBS in a previous pregnancy | 214 | 12 | IAP and broad spectrum* | 192 | IAP and broad spectrum* | 192 |
Incidental detection of maternal GBS carriage | 35 600 | 84 | IAP and broad spectrum* | 17 005 | IAP and broad spectrum* | 17 005 |
Pre-term delivery without the above risk factors | 55 446 | 134 | Broad spectrum* | 3041 | Broad spectrum* | 3041 |
Suspected intrapartum infection at term without the above risk factors | 13 036 | 69 | Broad spectrum* | 10 428 | Broad spectrum* in all, preceded by IAP in 2065 screen-positive women |
10 428 |
Term women with no antenatal or intrapartum risk factors indicating intrapartum antibiotic prophylaxis (IAP) (without screening) | 607 703 | 122 | N/A | 0 | IAP for women who screen group B Streptococcus GBS positive | 96 260 |
Summary | Baseline | Scenario 1 | Scenario 2 | |||
Totals for each scenario | Population | 800 327 women | Treated with antibiotics | 30 666 | Treated with antibiotics | 126 926 |
EOGBS cases | 421 | EOGBS cases prevented | 70 | EOGBS cases prevented | 122–127 | |
Deaths from EOGBS | 42 | Deaths from EOGBS prevented | 5 | Deaths from EOGBS prevented | 8 | |
Severe disability from EOGBS | 29 | Severe disability from EOGBS prevented | 5 | Severe disability from EOGBS prevented | 8–9 |
*Broad spectrum antibiotics given to those with suspected intrapartum infection.
N/A, not applicable.