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. 2019 Mar 23;9(3):e024324. doi: 10.1136/bmjopen-2018-024324

Table 6.

Model results

Risk group Outcomes before application of either prevention scenario (baseline) Scenario 1 (risk-based prevention) Scenario 2 (risk-based plus screening-based prevention)
Number of women in risk group Early onset GBS (EOGBS) cases Antibiotic type offered Number of women receiving antibiotics Antibiotic type offered Number of women receiving antibiotics
Neonate affected by EOGBS in a previous pregnancy 214 12 IAP and broad spectrum* 192 IAP and broad spectrum* 192
Incidental detection of maternal GBS carriage 35 600 84 IAP and broad spectrum* 17 005 IAP and broad spectrum* 17 005
Pre-term delivery without the above risk factors 55 446 134 Broad spectrum* 3041 Broad spectrum* 3041
Suspected intrapartum infection at term without the above risk factors 13 036 69 Broad spectrum* 10 428 Broad spectrum* in all, preceded by IAP in
2065 screen-positive women
10 428
Term women with no antenatal or intrapartum risk factors indicating intrapartum antibiotic prophylaxis (IAP) (without screening) 607 703 122 N/A 0 IAP for women who screen group B Streptococcus GBS positive 96 260
Summary Baseline Scenario 1 Scenario 2
Totals for each scenario Population 800 327 women Treated with antibiotics 30 666 Treated with antibiotics 126 926
EOGBS cases 421 EOGBS cases prevented 70 EOGBS cases prevented 122–127
Deaths from EOGBS 42 Deaths from EOGBS prevented 5 Deaths from EOGBS prevented 8
Severe disability from EOGBS 29 Severe disability from EOGBS prevented 5 Severe disability from EOGBS prevented 8–9

*Broad spectrum antibiotics given to those with suspected intrapartum infection.

N/A, not applicable.