Table 3.

Risk factors associated with thromboembolic events (PREvention oF thromboembolic events - European Registry in Atrial Fibrillation derivation cohort)

Variable	OR	95% CI	P value	Score
Abnormal liver function*	2.86	1.24 to 6.63	0.0141	2
Labile INR†	2.83	1.83 to 4.38	<0.0001	2
Drugs‡	2.41	1.58 to 3.69	<0.0001	1
Prior stroke/TIA/thromboembolic event	2.79	1.81 to 4.28	<0.0001	2
Heart failure	2.20	1.45 to 3.33	0.0002	1
Age ≥75 years	1.53	1.00 to 2.33	0.0482	1

*Presence of cirrhosis, elevated liver transaminases or alkaline phosphatase >3 times above the upper limit of normal (ULN), or bilirubin >2 times above the ULN.

†<60% time in therapeutic range.

‡Antiplatelet agents or non-steroidal anti-inflammatory drugs.

INR, international normalised ratio; TIA, transient ischaemic attack.