Fig. 1.

Light-producing V. fischeri induce gene expression in the light organ and the eye. Juvenile squids colonized with wild-type V. fischeri (SYM), but not those colonized with isogenic Δlux mutants (SYM-dark), induce profound gene expression in the light organ (including genes associated with the function of the eye) (1,283 genes) and, to a lower extent, in the eye (44 genes), but not in the gill (0 genes). One gene, ANP-CE, which is associated with cell swelling, was demonstrated to be expressed in crypt cells that undergo swelling after colonization with wild type, but not Δlux mutants. Adapted from data presented in figure 4 of ref. 2.