Table 3.
Functionality of C. eth-2.0 genes according to cellular processes
| Category | Functional C. eth-2.0 genes* | P value† |
| Translation‡ | 73.6% (81/110) | 5.49E-03 |
| Ribosomal proteins‡ | 60.6% (20/33) | 2.01E-03 |
| tRNA synthetases | 81.8% (18/22) | 6.14E-01 |
| tRNAs | 67.8% (19/28) | 4.73E-02 |
| Translation factors | 88.9% (24/27) | 2.22E-01 |
| Transcription | 86.7% (13/15) | 4.51E-01 |
| DNA replication | 83.9% (26/31) | 4.69E-01 |
| Cellular processes | 87.2% (123/141) | 1.12E-02 |
| Cell cycle | 87.5% (28/32) | 2.52E-01 |
| Cell envelope | 86.9% (73/84) | 8.48E-02 |
| Protein turnover | 88.0% (22/25) | 2.81E-01 |
| Energy production | 73.9% (34/46) | 1.03E-01 |
| Metabolism§ | 90.3% (121/134) | 2.60E-04 |
| Hypothetical proteins‡ | 64.2% (34/53) | 7.45E-04 |
| Total | 81.5% (432/530) |
*
Fraction of functional C. eth-2.0 genes as assessed by transposon sequencing. Numbers of functional genes vs. total gene numbers per class are shown in parentheses.
†
P values for functionality enrichment and deenrichment of different gene Categories.
‡
Categories of genes that display a significant decrease in functionality.
§
Categories of genes that display a significant increase in functionality.