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. 2019 Mar 4;116(16):7990–7999. doi: 10.1073/pnas.1819897116

Fig. 3.

Fig. 3.

Variation of symbiosis-responsive gene expression over the day/night cycle. Gene expression changes in SYM (compared with APO) light-organ (A), eye (B), and gill (C) tissue at different times of day: 0400 hours = 2 h before dawn; 1600 hours = 2 h before dusk; 2000 hours = 2 h after dusk. Juvenile squid were maintained for 3 d under a 12–12 light-dark schedule. Candidate genes where chosen for qRT-PCR based on expression changes observed at 72 h (SI Appendix, Fig. S9 and Table S1 and Dataset S4). BPI3, bactericidal/permeability-increasing protein 3. ***P < 0.001; **P < 0.01; *P <0.05; ·P < 0.1 (SYM vs. APO).