Table 5.
Comparison of raw score cut-offs in predicting impairment on both measures of verbal learning.
| 1.5 SD below the mean | 2.0 SD below the mean | ||||||
|---|---|---|---|---|---|---|---|
| RAVLT | CVLT-II | p-value | RAVLT | CVLT-II | p-value | ||
| Trial 1 | AUC | 0.76 (0.57, 0.95) | 0.67 (0.48, 0.85) | .229 | 0.84 (0.66, 1.00) | 0.75 (0.49, 1.00) | .751 |
| Sensitivity | 0.63 (0.26, 0.90) | 0.38 (0.10, 0.74) | .157 | 0.80 (0.30, 0.99) | 0.60 (0.17, 0.93) | .317 | |
| Specificity | 0.64 (0.53, 0.74) | 0.76 (0.66, 0.84) | .056 | 0.64 (0.54, 0.74) | 0.77 (0.67, 0.85) | .040 | |
| PPV | 0.13 (0.05, 0.29) | 0.12 (0.03, 0.32) | .798 | 0.11 (0.03, 0.26) | 0.12 (0.03, 0.32) | .697 | |
| NPV | 0.95 (0.86, 0.99) | 0.93 (0.84, 0.98) | .336 | 0.98 (0.90, 1.00) | 0.97 (0.89, 1.00) | .434 | |
| Trial 1+ 2 | AUC | 0.84 (0.70, 0.97) | 0.86 (0.75, 0.96) | .795 | 0.88 (0.72, 1.00) | 0.84 (0.68, 1.00) | .151 |
| Sensitivity | 0.75 (0.36, 0.96) | 0.88 (0.47, 0.99) | .317 | 0.80 (0.30, 0.99) | 0.60 (0.17, 0.93) | .317 | |
| Specificity | 0.76 (0.66, 0.84) | 0.77 (0.67, 0.85) | .835 | 0.65 (0.55, 0.75) | 0.81 (0.71, 0.88) | .009 | |
| PPV | 0.21 (0.09, 0.41) | 0.25 (0.11, 0.45) | .460 | 0.11 (0.04, 0.26) | 0.14 (0.04, 0.37) | .454 | |
| NPV | 0.97 (0.89, 1.00) | 0.99 (0.91, 1.00) | .310 | 0.98 (0.90, 1.00) | 0.97 (0.90, 1.00) | .464 | |
| Total Learning | AUC | 0.92 (0.84, 1.00) | 0.95 (0.90, 1.00) | .576 | 0.95 (0.86, 1.00) | 0.97 (0.94, 1.00) | .590 |
| Sensitivity | 0.88 (0.47, 0.99) | 0.88 (0.47, 0.99) | 1 | 1.00 (0.46, 1.00) | 1.00 (0.46, 1.00) | 1 | |
| Specificity | 0.77 (0.67, 0.85) | 0.85 (0.75, 0.91) | .127 | 0.76 (0.66, 0.84) | 0.93 (0.85, 0.97) | .002 | |
| PPV | 0.25 (0.11, 0.45) | 0.33 (0.15, 0.57) | .242 | 0.18 (0.07, 0.38) | 0.42 (0.16, 0.71) | .020 | |
| NPV | 0.99 (0.91, 1.00) | 0.99 (0.92, 1.00) | .947 | 1.00 (0.93, 1.00) | 1.00 (0.95, 1.00) | 1 | |
Notes. 95% confidence intervals are presented in parentheses.
Abbreviations: AUC= area under the curve; CVLT-II = California Verbal Learning Test - II; NPV = negative predictive value; PPV: = positive predictive value; RAVLT = Rey Auditory Verbal Learning Test.