Table 1.
Characteristics of the 1,044 patients with cirrhosis included in this study.
| Characteristics | All n=1,044 | By Frailty Status | p-value | ||
|---|---|---|---|---|---|
| Not Frail n=779 (75%) | Frail n=265 (25%) | ||||
| Age, years | 57 (49–63) | 57 (49–63) | 58 (51–63) | 0.07 | |
| Female | 43% | 41% | 46% | 0.16 | |
| Race/Ethnicity | Non-Hispanic White | 61% | 60% | 63% | 0.72 |
| Black | 4% | 4% | 5% | ||
| Hispanic | 23% | 24% | 21% | ||
| Asian/Pacific Islander | 4% | 5% | 3% | ||
| Other | 8% | 7% | 8% | ||
| Body mass index, kg/m2 | 28 (25–33) | 28 (25–33) | 28 (25–33) | 0.95 | |
| Etiology of liver disease | Chronic hepatitis C | 29% | 31% | 21% | <0.001 |
| Alcohol | 25% | 24% | 29% | ||
| Non-alcoholic steatohepatitis | 17% | 15% | 23% | ||
| Autoimmune/cholestatic | 16% | 18% | 11% | ||
| Other | 13% | 11% | 16% | ||
| Hypertension | 38% | 37% | 38% | 0.71 | |
| Diabetes | 30% | 26% | 42% | <0.001 | |
| Coronary artery disease | 5% | 6% | 3% | 0.11 | |
| MELDNa | 18 (15–22) | 18 (14–22) | 21 (16–25) | <0.001 | |
| Total bilirubin, mg/dL | 2.5 (1.6–4.2) | 2.5 (1.6–4.0) | 2.6 (1.5–4.8) | 0.68 | |
| Creatinine, mg/dL† | 0.9 (0.7–1.2) | 0.9 (0.7–1.2) | 1.0 (0.8–1.4) | <0.001 | |
| INR | 1.4 (1.2–1.6) | 1.4 (1.2–1.6) | 1.4 (1.3–1.7) | 0.15 | |
| Sodium, mEq/L | 137 (134–139) | 137 (134–139) | 136 (133–139) | 0.003 | |
| Albumin, g/dL | 3.1 (2.6–3.5) | 3.1 (2.6–3.5) | 3.0 (2.6–3.4) | 0.07 | |
| Dialysis | 5% | 3% | 11% | <0.001 | |
| Ascites | 36% | 32% | 48% | <0.001 | |
| Hepatic encephalopathy | 41% | 36% | 57% | <0.001 | |
| Outcome | Waiting | 44% | 47% | 35% | <0.001 |
| Death/delisted for being too sick for transplant | 18% | 15% | 26% | ||
| Deceased donor liver transplant | 27% | 26% | 27% | ||
| Other | 11% | 12% | 12% | ||
*
Median (interquartile range) or %
†
Among those who were not on dialysis