Table 3.
Univariable and step-wise additive multivariable models to assess associations between co-variables with mortality using competing risks models ((with deceased donor liver transplant as the competing risk) for the prims predictor of hepatic encephalopathy.
| Subhazard Ratios (95% CI) p-value | |||||
| Univariable | Multivariable models | ||||
| Hepatic encephalopathy | 1.84 (1.38–2.45) p<0.001 |
1.62 (1.21–2.19) p=0.001 |
1.60 (1.18–2.16) p=0.002 |
1.40 (1.03–1.91) p=0.03 |
1.31 (0.96–1.79) p=0.08 |
| Frail | 2.38 (1.77–3.20) p<0.001 |
2.11 (1.55–2.85) p<0.001 |
1.85 (1.35–2.55) p<0.001 |
1.82 (1.32–2.51) p<0.001 |
1.83 (1.33–2.52) p<0.001 |
| MELDNa, per point | 1.06 (1.04–1.09) p<0.001 |
1.04 (1.01–1.07) p=0.003 |
1.05 (1.02–1.08) p=0.001 |
1.04 (1.01–1.07) p=0.01 |
|
| Age | 1.03 (1.01–1.05) p=0.003 |
1.03 (1.01–1.05) p=0.01 |
1.03 (1.01–1.05) p=0.005 |
||
| Albumin, per g/dL | 0.64 (0.50–0.81) p<0.001 |
0.72 (0.54–0.94) p=0.02 |
|||
Variables evaluated for inclusion in the multivariable models were (because of p-value<0.2 in univariable analysis): age, female sex, Hispanic race, height, weight, dialysis, albumin. Only variables associated with a p-value <0.05 were retained in the fit models