Skip to main content
. Author manuscript; available in PMC: 2020 Apr 19.
Published in final edited form as: Org Lett. 2019 Feb 28;21(8):2493–2497. doi: 10.1021/acs.orglett.9b00508

Table 3.

Conversion of adducts 3a–3j to 4-methylenepyrrolidines 5a–5j via Tsuji-Trost allylation-Mitsunobu cyclization.a

graphic file with name nihms-1019068-t0007.jpg
a

Yields are of material isolated by silica gel chromatography. See Supporting Information for further experimental details.

b

After the first reaction was done, PPh3 (500 mol%), DIAD (500 mol%) and THF (0.05 M) were added at 25 °C, 12 h.