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. Author manuscript; available in PMC: 2020 Jan 9.
Published in final edited form as: J Am Chem Soc. 2018 Dec 26;141(1):148–153. doi: 10.1021/jacs.8b12520

Table 1.

Assessment of BINOL-Derived CPAs

graphic file with name nihms-1004571-t0011.jpg
entry CPA 3 (%) 4 (%) 5 (%) 6a (%) (% ee)
1 A 7 30 9  34 (96)
2 B 51 18 8 –
3 C 49 11 3 –
4 D 10 48 – –
5 E 8 36 10  36 (95)
6 F – 23 5  61 (99)
7b F – – –  72c (99)
a

1 H NMR yields determined using 1,2,4,5-tetramethylbenzene as internal standard.

b

Reaction temperature is 40 °C.

c

Isolated yield.