Table 3.
APTT, TT, anti-Xa and anti-IIa activities of unfractionated heparin (UFH), commercial LMWHs and LMWHs produced by US-Fenton system
| Sample | APTT* IU/mg | TT* IU/mg | Anti-FXa, IU/mg | Anti-FIIa, IU/mg | Anti-FXa/Anti-FIIa |
|---|---|---|---|---|---|
| UFP | 135 | 135 | 135 | 135 | 1 |
| LMWH-1 | 64.81±1.31 | 54.14±2.97 | 124.11 ± 3.21 | 81.42 ± 4.22 | 1.52 |
| LMWH-2 | 29.87±2.06 | <46.42 | 117.83 ± 4.17 | 44.76 ± 2.75 | 2.63 |
| LMWH-3 | 16.69±0.14 | <46.42 | 81.85 ± 2.84 | 41.73 ± 1.59 | 1.96 |
| LMWH-4 | <7.58 | <46.42 | 48.98 ± 2.17 | 37.33 ± 3.52 | 1.31 |
| Parnaparin | 27.64±5.35 | <46.42 | 106.64 ± 5.23 | 46.71 ± 2.94 | 2.28 |
| Enoxaparin | 29.21±3.00 | <46.42 | 138.03 ± 8.16 | 39.31 ± 2.33 | 3.51 |
| Nadroparin | 30.58±4.51 | <46.42 | 130.66 ± 1.39 | 50.33 ± 1.48 | 2.59 |
n = 3
The activities of agents to prolong APTT, PT, and TT are expressed by the concentration of each agent (IU/mg) that is required to double the APTT, PT, or TT.