Table 5.
Hematological values in male mice after 2 weeks of repeated oral administration of MO.
| Parameters | Group (mg/kg/day) | |||
|---|---|---|---|---|
| 0 | 50 | 150 | 450 | |
| RBC (× 106/μg) | 8.480 ±1.182 | 7.400 ± 2.224 | 8.680 ± 2.366 | 9.620 ± 0.554 |
| HB (g/dL) | 14.600 ±1.140 | 10.200 ± 3.347 | 12.600 ± 3.782 | 14.400 ± 0.894 |
| HCT (%) | 42.100 ± 11.520 | 36.480 ± 12.156 | 42.640 ± 12.182 | 47.680 ± 2.310 |
| MCV (fl) | 49.420 ± 1.099 | 48.820 ± 2.922 | 48.940 ± 1.122 | 49.640 ± 1.016 |
| MCH (pg) | 14.800 ± 0.447 | 14.200 ± 0.837 | 14.400 ± 0.894 | 14.800 ± 0.447 |
| MCHC (g/dL) | 29.880 ± 0.879 | 28.200 ± 2.021 | 28.860 ± 1.252 | 29.620 ± 0.610 |
| PLT (× 103/μg) | 729.400 ± 122.100 | 685.200 ± 249.905 | 661.000 ± 83.382 | 715.800 ± 65.370 |
| WBC (× 103/μg) | 2.240 ± 1.314 | 2.720 ± 1.224 | 2.320 ± 1.274 | 3.160 ± 1.383 |
| NEU (%) | 15.320 ± 9.066 | 10.200 ± 1.495 | 17.360 ± 8.914 | 21.180 ± 15.790 |
| LYM (%) | 79.140 ± 11.305 | 84.960 ± 3.087 | 76.440 ± 9.095 | 74.360 ± 17.568 |
| MON (%) | 3.300 ± 0.846 | 3.280 ± 1.152 | 3.440 ± 1.410 | 2.960 ± 1.601 |
| EOS (%) | 1.640 ± 2.263 | 1.100 ± 1.177 | 1.860 ±1.633 | 1.040 ± 1.488 |
| BAS (%) | 0.620 ± 0.567 | 0.480 ± 0.634 | 0.900 ± 0.552 | 0.460 ± 0.650 |
RBC, red blood cells; HB, hemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin;
MCHC, mean corpuscular hemoglobin concentration; PLT, platelet; WBC, white blood cell; NEU, neutrophil; LYM, lymphocyte;
MON, monocyte; EOS, eosinophil; BAS, basophil.
Values are expressed as means ± SD of five mice at sacrifice.