Table 3.
Effect of TTEP on the T lymphocyte subgroups of BCG/LPS induced live injury (, n=10).
| Group | CD3+ (%) | CD4+ (%) | CD8+ (%) | CD4+ / CD8+ (%) |
|---|---|---|---|---|
| Control | 76.1 ± 6.4 | 52.5 ± 6.0 | 24.9 ± 6.8 | 2.11 ± 0.42 |
| Model | 38.6 ± 4.2## | 32.6 ± 5.8## | 45.7 ± 7.9# | 0.71 ± 0.08## |
| Bifendate | 62.3 ± 7.5∗∗ | 43.7 ± 8.1∗∗ | 28.6 ± 7.3∗ | 1.52 ± 0.41∗∗ |
| TFEP 50 mg/Kg | 43.5 ± 5.6 | 35.5 ± 5.1 | 36.7 ± 8.3 | 0.96 ± 0.17∗ |
| 100 mg/Kg | 56.4 ± 7.3∗ | 39.1 ± 6.3∗ | 32.3 ± 6.7∗ | 1.21 ± 0.36∗∗ |
| 200 mg/Kg | 67.7 ± 5.4∗∗ | 45.0 ± 7.4∗∗ | 27.1 ± 5.8∗ | 1.66 ± 0.49∗∗ |
Anticoagulated blood was treated with erythrocyte lysate to get the lymphocyte suspension and then incubated with CD3+, CD4+, and CD8+ antibody before analysis with flow cytometry. ∗P < 0.05, ∗∗P < 0.01 compared with the model group; #P<0.05, ##P<0.01 compared with the control group.