Table 4.
Effect of TTEP on serum levels of ALT, AST, and ALP (, n=10).
| Group | ALT (U/L) | AST (U/L) | ALP (U/L) |
|---|---|---|---|
| Control | 36.2 ± 9.0 | 43.0 ± 16.8 | 87.6 ± 10.4 |
| Model | 158.2 ± 32.3## | 163.7 ± 13.6## | 162.6 ± 16.9## |
| Bifendate | 95.0 ± 16.9∗∗ | 105.7 ± 8.1∗∗ | 115.6 ± 12.3∗∗ |
| TTEP 50 mg/Kg | 123.6 ± 20.7∗ | 122.5 ± 15.1∗ | 143.7 ± 13.6 |
| 100 mg/Kg | 105.2 ± 20.1∗∗ | 105.1 ± 10.3∗∗ | 132.3 ± 9.7∗∗ |
| 200 mg/Kg | 82.4 ± 19.0∗∗ | 79.8 ± 10.6∗∗ | 112.1 ± 15.8∗∗ |
Mouse blood samples were centrifuged to get the serum, and alanine aminotransferase (ALT), aspartate transaminase (AST), and alkaline phosphatase (ALP) activities were detected by colorimetric method. ∗P < 0.05, ∗∗P < 0.01 compared with the model group; #P<0.05, ##P<0.01 compared with the control group.