Table 5.
Effect of TTFP on TNF-α, IL-6, and NO of immunological liver injury mice (, n=10).
| Group | TNF-α (pg/mL) |
IL-6 (pg/mL) |
NO (μmol/gprot) |
|---|---|---|---|
| Control | 63.4 ± 16.8 | 37.3 ± 8.4 | 1.47 ± 0.36 |
| Model | 39.7 ± 11.0## | 143.6 ± 26.5## | 3.62 ± 0.64# |
| Bifendate | 55.6 ± 12.4∗∗ | 66.1 ± 13.3∗ | 1.94 ± 0.47∗∗ |
| TTEP 50 mg/Kg | 42.4 ± 13.1 | 102.4 ± 19.7∗ | 2.85 ± 0.43∗ |
| 100 mg/Kg | 50.7 ± 14.3∗ | 87.6 ± 15.2∗∗ | 2.30 ± 0.52∗∗ |
| 200 mg/Kg | 58.3 ± 12.9∗∗ | 55.7 ± 10.7∗∗ | 1.91 ±.051∗∗ |
Mouse liver samples were homogenized with icy saline and centrifuged to get the supernatants. The levels of TNF-α and IL-6 were detected with ELISA kits, while NO contents were detected by Griess Reagent Assay. ∗P < 0.05, ∗∗P < 0.01 compared with the model group; #P<0.05, ##P<0.01 compared with the control group.