Table 1.

Effects of antibody on probability of chlamydia ascension to the endometrium determined by causal mediator analysis.

Antibody Subtype	Average indirect effect or causal mediator effect through burden		Average direct effect independent of burden		Average total effect
	(95% CI)	P Value	(95% CI)	P Value	(95% CI)	P Value
Serum IgG	−0.11#		0.055		−0.055
	(−0.19, −0.04)	0.001	(−0.1, 0.2)	0.445	(−0.2, 0.1)	0.496
Serum IgA	−0.02		−0.04		−0.06
	(−0.05, 0.01)	0.180	(−0.16, 0.07)	0.452	(−0.18, 0.05)	0.296
Cervix IgG	−0.07		0.15		0.08
	(−0.17, 0.01)	0.082	(−0.05, 0.33)	0.128	(−0.13, 0.27)	0.449
Cervix IgA	−0.12		0.09		−0.03
	(−0.22, −0.03)	0.002	(−0.17, 0.31)	0.459	(−0.29, 0.23)	0.845

^#Each value represents the percent decreased (-values) or increased (+values) probability of ascension. For example, there is an 11% decreased risk of ascension for women with a specific serum anti-EB IgG response.