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. 2019 Apr 15;11(4):335–347. doi: 10.4251/wjgo.v11.i4.335

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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Immunohistochemical staining of human epidermal growth factor receptor 2. A,B: Immunohistochemical staining of human epidermal growth factor receptor 2 in most colorectal adenocarcinomas (CRCs) was scored as either 0 (A) or 1+ (B); C: Approximately 9% of CRCs exhibited 2+ staining; D: Only 2.6% of CRCs exhibited 3+ staining.