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Concordance between human epidermal growth factor receptor 2 overexpression by Immunohistochemical staining and human epidermal growth factor receptor 2 gene amplification by fluorescence in situ hybridization
| IHC score |
HER2 gene amplification (FISH) |
% HER2 gene amplification | |
| Positive | Negative | ||
| 1+ (n = 10) | 0 | 10 | 0% |
| 2+ (n = 102) | 12 | 90 | 11.8% |
| 3+ (n = 29) | 24 | 5 | 82.8% |
HER2: Human epidermal growth factor receptor 2; FISH: Fluorescence in situ hybridization; IHC: Immunohistochemical staining.
