. 2019 Mar 7;7(4):1482–1493. doi: 10.1002/fsn3.988

Table 1.

Blood glucose and body weight changes over 4 weeks of intervention

Rat groups	Baseline	Week 1	Week 2	Week 3	Week 4
Glucose (mM)
C. nutans 100 mg/kg	18.6 ± 0.7^a	14.6 ± 2.8^a ^, ^b	14.0 ± 2.2^a	14.2 ± 2.1^a	14.2 ± 2.1^a
C. nutans 200 mg/kg	19.5 ± 0.81^a	14.5 ± 2.1^a ^, ^b	15.4 ± 4.2^a	15.0 ± 2.1^a	14.1 ± 4.2^a
Quercetin 10 mg/kg	19.8 ± 4.1^a	14.8 ± 3.4^a	16.8 ± 1.2^a	20.0 ± 4.3^a	19.9 ± 4.2^a
Diabetic control	18.2 ± 0.8^a	15.2 ± 1.8^a	17.7 ± 2.3^a	18.3 ± 1.6^a	22.1 ± 4.8^a
Normal	4.7 ± 0.5	4.2 ± 0.2	5.3 ± 1.3	5.3 ± 0.9	5.2 ± 0.8
Weight (g)
C. nutans 100 mg/kg	326 ± 30^a	293 ± 40^a	282 ± 44^a	283 ± 45^a	279 ± 44^a ^, ^b
C. nutans 200 mg/kg	306 ± 30^a	273 ± 29^a	287 ± 21^a	291 ± 30^a	290 ± 40^a ^, ^b
Quercetin 10 mg/kg	322 ± 57	302 ± 44	297 ± 53	303 ± 52	296 ± 48
Diabetic control	311 ± 21	278 ± 29	261 ± 39	261 ± 38	258 ± 38^a
Normal	270 ± 21	288 ± 24	303 ± 25	316 ± 25	325 ± 26

Data are mean ± SD (n = 5). The normal group was fed normal pellet throughout the intervention, while the diabetic control group (high‐fat diet + 35 mg/kg streptozotocin) received high‐fat diet for 4 weeks. The quercetin, C. nutans 100 mg and C. nutans 200 mg groups received quercetin (10 mg kg⁻¹ day⁻¹), and 100 mg kg⁻¹ day⁻¹ and 200 mg kg⁻¹ day⁻¹ of aqueous extract of Clinacanthus nutans in addition to the high‐fat diet for 4 weeks after diabetes induction.

Statistical difference in comparison with the normal group for either glucose or weight measurements in each column (p < 0.05).

Statistical difference in comparison with the diabetic control normal group in each row (p < 0.05).